7 Best Hydrating Serums We Tested 2026, Approved by Dermatologists


Hyaluronic acid, glycerin, and ceramides are considered highly effective for lasting hydration, says Yulia Krasnaya, MD, a dermatologist at Evolution Aesthetics Clinic.

Hyaluronic acid is a potent humectant, capable of holding water molecules and providing intense hydration. Glycerin is also a humectant that attracts and retains moisture, helping to keep the skin hydrated,” says Mahsa Saleki, MD, an aesthetic doctor and surgeon at SAS Aesthetics.

And if your skin is dehydrated (i.e flaky or cracked) a more intense hydrating serum might be needed. If this is the case, consider formulas containing beta-glucan. “Beta-glucan is 20% more hydrating than hyaluronic acid,” says Christine Hall MD, a general practitioner in medical aesthetics registered with the UK’s General Medical Council. It’s derived from bacteria, fungi, seaweed, and grains like oats. It’s a humectant that also has antioxidant and anti-inflammatory properties, meaning that it will help to restore and repair skin barrier.

You can also opt for a serum with ceramides. Ceramides are lipids, molecules, or fats that ensure that our skin barrier remains strong and prevents transepidermal water loss, or water loss through the skin barrier, Dr. Hall recommends. Additionally, aloe vera is great for soothing and hydrating, niacinamide improves the skin’s barrier function, and panthenol attracts and holds moisture.



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