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Why Do Mind-Altering Drugs Make People Feel Better?

When Olson was at Stanford, he learned from a mentor who had honed a new method for developing drugs: function-oriented synthesis. Within a given molecule, specific groups of atoms could be catalogued according to their individual effects on the body. If you determined which group did what, then you could potentially synthesize a compound that … Read more

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“Project Hail Mary” Movie: A Review of a Sci-Fi Comedy

Enter Eva Stratt (Sandra Hüller), a government official with a barbed half smile and a will of iron, who drags Grace back to the world of top-flight science, which he left behind years before, after flaming out of academia. Stratt is the head of Project Hail Mary, a global rescue effort to stop the star-eaters … Read more

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Two Playwrights Tackle Father Figures

Still, the most remarkable performance at the Cherry Lane is by Peter Friedman, who plays the kind of father you rarely see in art: a good one. It’s a hard sort of acting to describe, a spectacle of humility and self-awareness, unshowy and confident. A businessman with a genial, chatty energy, Mae’s father, facing mortality, … Read more

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A New Oscar for Best Casting

new video loaded: A New Oscar for Best Casting This year, there’s a new category at the Oscars: the Academy Award for best achievement in casting. Our reporter Esther Zuckerman spoke with all five nominees to find out what makes good casting. By Esther Zuckerman, Léo Hamelin, Laura Salaberry and Edward Vega March 12, 2026

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Patricia Cornwell on Crime and Creativity

The crime novelist Patricia Cornwell has written more than forty books, which have altogether sold more than a hundred and twenty million copies. (This week, a long-awaited adaptation of her “Scarpetta” series, which centers on a forensic pathologist, premières on Amazon, with Nicole Kidman in the title role.) How does she do it? “I learned … Read more

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War in the Age of the Online “Information Bomb”

On TikTok, the war against Iran began with a series of videos from influencer types in Dubai, Doha, and elsewhere in the Middle East. They sat on restaurant patios or on hotel-room balconies and pointed their phone cameras skyward to document missiles flying through the air of their respective cities, then disappearing into puffs of … Read more

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The Creator of Wordle Tries to Solve the Cryptic Crossword

Wardle had tried cryptic crosswords when he was younger, but found them to be impenetrable. “I didn’t know how to begin,” he told me. The rules could seem arcane, almost impossible to deduce. A clue containing the word “radio” could signal that “am” or “fm” belongs somewhere in the answer; “book” could imply “ot” or … Read more

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